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Founders · Sunday, 12 July 2026 · Issue 40 · 9 stories

Nvidia's GPU Loans Raise AI Doubts, Yosemite Bets $350M

Funding & VC

Yosemite’s $350M fund aims to rewrite cancer drug pipeline with AI

Reed Jobs says Yosemite’s second fund closed at $350 million, earmarked for building biotech startups that turn academic breakthroughs into cancer cures. The firm now has 17 staff, leverages AI for drug discovery and clinical trials, and splits capital, about a third into companies it creates itself. Blockbuster patent cliffs and AI progress are expanding the opportunity.

techcrunch.com ↗11 min read at source

Building the Company

AI’s “Magic Box” Is Anything But Simple, The Hidden Engineering Burden

Tom Tunguz shows that today’s LLM‑powered apps still require massive pipelines, tool‑orchestration, observability, and guardrails, essentially the same hidden infrastructure that plagued 2015 ML systems. The hidden technical debt now lives in data stores, retrieval‑augmented generation, and cost‑control layers, turning promised simplicity into an iceberg of engineering work.

tomtunguz.com ↗2 min read at source

Growth & GTM

Leadership & Lessons

Why coding still matters in 2026 despite AI‑generated code

Doug argues that writing code remains a vital thinking tool, not a production task, because it forces engineers to engage directly with execution details that AI can miss. He warns that neglecting hands‑on coding erodes system fragility and team ownership, affecting long‑term reliability of AI‑assisted development.

softwaredoug.com ↗4 min read at source

You’re caught up.

That was all 9 stories in the 12 July issue.