AI model adds 18 new rare‑disease diagnoses to stalled child cases
OpenAI’s o3 Deep Research model re‑examined 376 unsolved pediatric rare‑disease cases and helped clinicians confirm 18 new genetic diagnoses, boosting yield by 4.8%. The AI supplied evidence‑linked hypotheses, letting experts focus testing on the most promising leads and showing how periodic AI‑assisted reanalysis can unlock hidden answers.