Bayer’s PRINCE shows how to engineer reliable LLM agents for drug research
Bayer and Thoughtworks built PRINCE, a cloud platform that lets scientists query decades of preclinical safety data with natural-language LLM agents backed by retrieval-augmented generation and Text-to-SQL. The case study details engineering choices—context engineering, orchestration, recovery, observability, and human-in-the-loop controls—that keep the system reliable and auditable, cutting research time dramatically.